Version 5.4
Mus musculus Gene: Fancg
Summary
InnateDB Gene IDBG-139854.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fancg
Gene Name Fanconi anemia, complementation group G
Synonyms AU041407; Xrcc9
Species Mus musculus
Ensembl Gene ENSMUSG00000028453
Encoded Proteins
IDBP-139856
Fanconi anemia, complementation group G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000221829:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:43002343-43010506
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000030165 ENSMUSP00000030165
ENSMUST00000123332
ENSMUST00000148018
ENSMUST00000124645
ENSMUST00000127067
ENSMUST00000125570
ENSMUST00000134083
ENSMUST00000135362
ENSMUST00000133915
ENSMUST00000132273
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001541 ovarian follicle development
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007005 mitochondrion organization
GO:0007286 spermatid development
GO:0009314 response to radiation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0043240 Fanconi anaemia nuclear complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000221829
View Gene Order
ENSBTAG00000015005
Not yet available
Pathways
NETPATH
REACTOME
REACT_233397
DNA Repair pathway
REACT_232842
Fanconi Anemia pathway pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18410
Fanconi Anemia pathway pathway
REACT_216
DNA Repair pathway
KEGG
INOH
PID NCI
fanconi_pathway
Fanconi anemia pathway
bard1pathway
BARD1 signaling events
Cross-References
SwissProt Q9EQR6
TrEMBL Q8VHS1
UniProt Splice Variant
Entrez Gene 60534
UniGene Mm.23122 Mm.407142 Mm.488375
RefSeq NM_001163233 NM_053081 XM_006538127 XM_006538128
OMIM
CCDS CCDS18087
HPRD
IMGT
MGI ID MGI:1926471
MGI Symbol Fancg
EMBL AF112439 AH011363 AL672276 AY049715
GenPept AAG43198 AAL12165 AAL60156 CAM14317
RNA Seq Atlas 60534

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca