Version 5.4
Mus musculus Gene: Lgsn
Summary
InnateDB Gene IDBG-140173.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lgsn
Gene Name lengsin, lens protein with glutamine synthetase domain
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050217
Encoded Proteins
IDBP-140175
lengsin, lens protein with glutamine synthetase domain
IDBP-788587
lengsin, lens protein with glutamine synthetase domain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146166:
This gene encodes a protein with similarity to the GS I members of the glutamine synthetase superfamily. The encoded protein is referred to as a pseudo-glutamine synthetase because it has no glutamine synthesis activity and may function as a chaperone protein. This protein is localized to the lens and may be associated with cataract disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:31176401-31204725
Strand Forward strand
Band B
Transcripts
ENSMUST00000062560 ENSMUSP00000059871
ENSMUST00000161773 ENSMUSP00000140063
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004356 glutamate-ammonia ligase activity
GO:0005515 protein binding
Biological Process
GO:0006542 glutamine biosynthetic process
GO:0006807 nitrogen compound metabolic process
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146166
View Gene Order
ENSBTAG00000010051
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 266744
UniGene
RefSeq NM_153601
OMIM
CCDS CCDS14859
HPRD
IMGT
MGI ID MGI:2672844
MGI Symbol Lgsn
EMBL
GenPept
RNA Seq Atlas 266744

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca