Mus musculus Gene: Pcdhgc5
Summary
InnateDB Gene IDBG-140386.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdhgc5
Gene Name protocadherin gamma subfamily A, 3
Synonyms mKIAA4054; pc2c; PC43; Pcdh13; Pcdh2
Species Mus musculus
Ensembl Gene ENSMUSG00000023036
Encoded Proteins
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
protocadherin gamma subfamily C, 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000240764:
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37674335-37841873
Strand Forward strand
Band B3
Transcripts
ENSMUST00000003599 ENSMUSP00000003599
ENSMUST00000073447 ENSMUSP00000073150
ENSMUST00000066149 ENSMUSP00000067728
ENSMUST00000091935 ENSMUSP00000089555
ENSMUST00000044851 ENSMUSP00000036359
ENSMUST00000076807 ENSMUSP00000076085
ENSMUST00000061279 ENSMUSP00000058362
ENSMUST00000066140 ENSMUSP00000068846
ENSMUST00000055935 ENSMUSP00000060949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL Q5DTQ9 Q8K4A0 Q8K4A4 Q8K4A6 Q91XW9 Q91XX0 Q91XX1 Q91XX4 Q91XX9 Q91XY0 Q91XY5 Q91XY7 Q91XY8
UniProt Splice Variant
Entrez Gene 93724
UniGene Mm.414190
RefSeq NM_033578 NM_033581 NM_033582 NM_033583 NM_033586 NM_033591 NM_033592 NM_033594 NM_033595
OMIM
CCDS CCDS29191 CCDS29192 CCDS29193 CCDS29194 CCDS37781 CCDS37782 CCDS37783 CCDS37784 CCDS50259
HPRD
IMGT
MGI ID MGI:1935197 MGI:1935201 MGI:1935203 MGI:1935205 MGI:1935215 MGI:1935221 MGI:1935226 MGI:1935228 MGI:1935229
MGI Symbol Pcdhga11 Pcdhga12 Pcdhga3 Pcdhga8 Pcdhga9 Pcdhgb6 Pcdhgc3 Pcdhgc4 Pcdhgc5
EMBL AC020971 AC129315 AF464156 AF464158 AF464163 AF464165 AK220461 AY013794 AY013795 AY013797 AY013802 AY013803 AY013808 AY013811 AY013812 AY013813 BC054528 BC054556 BC054787 BC056998 BC059175 BC059837 BC060691 BC064675 BC064808 BC079567 BC138677 BC138678 CH466528
GenPept AAH54528 AAH54556 AAH54787 AAH56998 AAH59175 AAH59837 AAH60691 AAH64675 AAH64808 AAH79567 AAI38678 AAI38679 AAK26083 AAK26084 AAK26086 AAK26091 AAK26092 AAK26097 AAK26100 AAK26101 AAK26102 AAM93559 AAM93561 AAM93564 AAM93566 BAD90279 EDL10123 EDL10130 EDL10131 EDL10135
RNA Seq Atlas 93703 93706 93707 93708 93711 93716 93717 93723 93724