Mus musculus Gene: Dnm2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-140436.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Dnm2 | ||||||||||||||||||||||
Gene Name | dynamin 2 | ||||||||||||||||||||||
Synonyms | b2b2159Clo; Dyn2; Udnm | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000033335 | ||||||||||||||||||||||
Encoded Proteins |
dynamin 2
dynamin 2
dynamin 2
dynamin 2
dynamin 2
dynamin 2
dynamin 2
dynamin 2
dynamin 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079805:
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 9:21424908-21507759 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | A3 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 75 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Innate Immune System pathway
Gap junction trafficking and regulation pathway
eNOS activation and regulation pathway
Recycling pathway of L1 pathway
Membrane Trafficking pathway
NOSTRIN mediated eNOS trafficking pathway
Formation of annular gap junctions pathway
Metabolism pathway
Lysosome Vesicle Biogenesis pathway
Immune System pathway
Golgi Associated Vesicle Biogenesis pathway
Retrograde neurotrophin signalling pathway
MHC class II antigen presentation pathway
Gap junction degradation pathway
Axon guidance pathway
Toll-Like Receptors Cascades pathway
trans-Golgi Network Vesicle Budding pathway
L1CAM interactions pathway
Clathrin derived vesicle budding pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Developmental Biology pathway
Metabolism of nitric oxide pathway
NGF signalling via TRKA from the plasma membrane pathway
Gap junction trafficking pathway
Signal Transduction pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
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KEGG |
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
Bacterial invasion of epithelial cells pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TCR pathway
BCR pathway
IL5 pathway
Prolactin pathway
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REACTOME |
Toll Like Receptor 4 (TLR4) Cascade pathway
MHC class II antigen presentation pathway
Retrograde neurotrophin signalling pathway
NOSTRIN mediated eNOS trafficking pathway
Formation of annular gap junctions pathway
Gap junction degradation pathway
Lysosome Vesicle Biogenesis pathway
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
Developmental Biology pathway
Signalling by NGF pathway
trans-Golgi Network Vesicle Budding pathway
eNOS activation and regulation pathway
Innate Immune System pathway
Metabolism of nitric oxide pathway
Toll-Like Receptors Cascades pathway
Axon guidance pathway
Signal Transduction pathway
Gap junction trafficking pathway
Adaptive Immune System pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
Metabolism pathway
Gap junction trafficking and regulation pathway
Membrane Trafficking pathway
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KEGG |
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
Bacterial invasion of epithelial cells pathway
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INOH | |||||||||||||||||||||||
PID NCI |
Signaling events mediated by VEGFR1 and VEGFR2
Syndecan-4-mediated signaling events
Arf6 trafficking events
PDGFR-beta signaling pathway
Posttranslational regulation of adherens junction stability and dissassembly
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | G3UY64 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 13430 | ||||||||||||||||||||||
UniGene | Mm.433257 | ||||||||||||||||||||||
RefSeq | NM_001039520 NM_001253893 NM_001253894 NM_007871 XM_006509977 XM_006509979 XM_006509980 XM_006509981 XM_006509982 XM_006509986 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS57657 CCDS57658 CCDS57659 CCDS57660 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:109547 | ||||||||||||||||||||||
MGI Symbol | Dnm2 | ||||||||||||||||||||||
EMBL | AC163748 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 13430 | ||||||||||||||||||||||