Mus musculus Gene: Fpr2
Summary
InnateDB Gene IDBG-141095.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fpr2
Gene Name formyl peptide receptor 2
Synonyms E330010I07Rik; Fpr-rs2
Species Mus musculus
Ensembl Gene ENSMUSG00000052270
Encoded Proteins
formyl peptide receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] FPR1 and FPR2 are G-protein-coupled receptors that recognize bacterial signal peptides, constituting a novel class of immune activators that contribute to mammalian immune defence against bacteria.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171049:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:17887824-17893952
Strand Forward strand
Band A3.2
Transcripts
ENSMUST00000064068 ENSMUSP00000065799
ENSMUST00000149944
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004982 N-formyl peptide receptor activity
Biological Process
GO:0006935 chemotaxis
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
Formyl peptide receptors bind formyl peptides and many other ligands pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Staphylococcus aureus infection pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (i) signalling events pathway
Formyl peptide receptors bind formyl peptides and many other ligands pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Staphylococcus aureus infection pathway
INOH
PID NCI
Cross-References
SwissProt O88536
TrEMBL
UniProt Splice Variant
Entrez Gene 14289
UniGene Mm.416226
RefSeq NM_008039
OMIM
CCDS CCDS28419
HPRD
IMGT
MGI ID MGI:1278319
MGI Symbol Fpr2
EMBL AF071180 AY138248 BC117066 CH466642
GenPept AAC34585 AAI17067 AAN06932 EDL20513
RNA Seq Atlas 14289