Version 5.4
Mus musculus Gene: Ufd1l
Summary
InnateDB Gene IDBG-142494.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ufd1l
Gene Name ubiquitin fusion degradation 1 like
Synonyms Ufd1
Species Mus musculus
Ensembl Gene ENSMUSG00000005262
Encoded Proteins
IDBP-142496
ubiquitin fusion degradation 1 like
IDBP-249307
ubiquitin fusion degradation 1 like
IDBP-625783
ubiquitin fusion degradation 1 like
IDBP-625786
ubiquitin fusion degradation 1 like
IDBP-625802
ubiquitin fusion degradation 1 like
IDBP-625803
ubiquitin fusion degradation 1 like
IDBP-625806
ubiquitin fusion degradation 1 like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070010:
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:18811779-18835261
Strand Forward strand
Band A3
Transcripts
ENSMUST00000005394 ENSMUSP00000005394
ENSMUST00000115578 ENSMUSP00000111241
ENSMUST00000168822 ENSMUSP00000130394
ENSMUST00000172013 ENSMUSP00000128186
ENSMUST00000164795
ENSMUST00000171789 ENSMUSP00000131977
ENSMUST00000163695 ENSMUSP00000132341
ENSMUST00000166352
ENSMUST00000172451 ENSMUSP00000133217
ENSMUST00000170325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000070010
View Gene Order
ENSBTAG00000004284
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.237594 Mm.396070 Mm.487938
RefSeq NM_011672 XM_006522005 XM_006522006 XM_006536818 XM_006536819
OMIM
CCDS CCDS28028
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca