Mus musculus Gene: Serpinb6a | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-143524.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Serpinb6a | ||||||
Gene Name | serine (or cysteine) peptidase inhibitor, clade B, member 6a | ||||||
Synonyms | 4930482L21Rik; D330015H01Rik; ovalbumin; PI-6; Serpinb6; Spi3 | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000060147 | ||||||
Encoded Proteins |
serine (or cysteine) peptidase inhibitor, clade B, member 6c
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
serine (or cysteine) peptidase inhibitor, clade B, member 6a
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124570:
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 13:33917918-34002794 | ||||||
Strand | Reverse strand | ||||||
Band | A3.3 | ||||||
Transcripts | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
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Gene ID
Gene Order
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Pathways | |||||||
NETPATH | |||||||
REACTOME | |||||||
KEGG |
Amoebiasis pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Dissolution of Fibrin Clot pathway
Hemostasis pathway
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KEGG |
Amoebiasis pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | Mm.252210 | ||||||
RefSeq | NM_001164117 NM_001164118 NM_001243192 NM_009254 XM_006516623 XM_006516624 | ||||||
OMIM | |||||||
CCDS | CCDS26441 CCDS49228 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | |||||||
MGI Symbol | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||