Version 5.4
Mus musculus Gene: Syt7
Summary
InnateDB Gene IDBG-143854.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syt7
Gene Name synaptotagmin VII
Synonyms AI851541; B230112P13Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024743
Encoded Proteins
IDBP-143858
synaptotagmin VII
IDBP-143860
synaptotagmin VII
IDBP-619925
synaptotagmin VII
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000011347:
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10389090-10453181
Strand Forward strand
Band A
Transcripts
ENSMUST00000076968 ENSMUSP00000076234
ENSMUST00000073899 ENSMUSP00000073560
ENSMUST00000169121 ENSMUSP00000127973
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001778 plasma membrane repair
GO:0006887 exocytosis
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0050796 regulation of insulin secretion
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0031045 dense core granule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000011347
View Gene Order
ENSBTAG00000019947
Not yet available
Cross-References
SwissProt
TrEMBL Q8CF96
UniProt Splice Variant
Entrez Gene 54525
UniGene Mm.182654 Mm.405112
RefSeq NM_173067 XM_006527210 NM_018801 NM_173068 XM_006527203 XM_006527204 XM_006527205 XM_006527206 XM_006527207 XM_006527208 XM_006527209 XM_006527211
OMIM
CCDS CCDS29576 CCDS29575 CCDS50388
HPRD
IMGT
MGI ID MGI:1859545
MGI Symbol Syt7
EMBL AB075900 AC124169
GenPept BAC44832
RNA Seq Atlas 54525

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca