InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc27a5

Summary

InnateDB Gene

IDBG-143911.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc27a5

Gene Name

solute carrier family 27 (fatty acid transporter), member 5

Synonyms

FACVL3; FATP5; Vlacsr; VLCS-H2; VLCSH2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030382

Encoded Proteins

IDBP-143913

solute carrier family 27 (fatty acid transporter), member 5

IDBP-401567

solute carrier family 27 (fatty acid transporter), member 5

IDBP-538401

solute carrier family 27 (fatty acid transporter), member 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083807:
The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:12988346-12998192

Strand

Reverse strand

Band

Transcripts

ENSMUST00000032539	ENSMUSP00000032539
ENSMUST00000120903	ENSMUSP00000112495
ENSMUST00000129268
ENSMUST00000133977	ENSMUSP00000117208
ENSMUST00000155192

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004467	long-chain fatty acid-CoA ligase activity
GO:0005524	ATP binding
GO:0015245	fatty acid transporter activity
GO:0031957	very long-chain fatty acid-CoA ligase activity
GO:0032403	protein complex binding
GO:0047747	cholate-CoA ligase activity

Biological Process

GO:0000038	very long-chain fatty acid metabolic process
GO:0001676	long-chain fatty acid metabolic process
GO:0006642	triglyceride mobilization
GO:0006699	bile acid biosynthetic process
GO:0008152	metabolic process
GO:0008206	bile acid metabolic process
GO:0015908	fatty acid transport
GO:0015911	plasma membrane long-chain fatty acid transport
GO:0046951	ketone body biosynthetic process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0009925	basal plasma membrane
GO:0030176	integral component of endoplasmic reticulum membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0043234	protein complex