InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Pkmyt1

Summary

InnateDB Gene

IDBG-143989.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pkmyt1

Gene Name

protein kinase, membrane associated tyrosine/threonine 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000023908

Encoded Proteins

IDBP-143991

protein kinase, membrane associated tyrosine/threonine 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127564:
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:23726336-23736729

Strand

Forward strand

Band

A3.3

Transcripts

ENSMUST00000024701

ENSMUSP00000024701

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0046872	metal ion binding