Mus musculus Gene: Npsr1
Summary
InnateDB Gene IDBG-144387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Npsr1
Gene Name neuropeptide S receptor 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000043659
Encoded Proteins
neuropeptide S receptor 1
neuropeptide S receptor 1
neuropeptide S receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187258:
This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:24097996-24316398
Strand Forward strand
Band A3
Transcripts
ENSMUST00000059650 ENSMUSP00000056432
ENSMUST00000133787 ENSMUSP00000117786
ENSMUST00000154644 ENSMUSP00000115126
ENSMUST00000154337
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005000 vasopressin receptor activity
GO:0008188 neuropeptide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
G alpha (s) signalling events pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (s) signalling events pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BZP8
TrEMBL A1KXK3 A6X922 B1B1A4
UniProt Splice Variant
Entrez Gene 319239
UniGene Mm.130824
RefSeq NM_175678 XM_006510400 XM_006510401 XM_006510402
OMIM
CCDS CCDS22930
HPRD
IMGT
MGI ID MGI:2441738
MGI Symbol Npsr1
EMBL AC132104 AC155635 AK033957 AK041451 AY255574 AY299387 CH466522 CT010514
GenPept AAO85086 AAQ75583 BAC28526 BAC30949 EDL25284 EDL25285
RNA Seq Atlas 319239