InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: YKT6

Summary

InnateDB Gene

IDBG-14464.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

YKT6

Gene Name

YKT6 v-SNARE homolog (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000106636

Encoded Proteins

IDBP-14466

YKT6 v-SNARE homolog (S. cerevisiae)

IDBP-373778

YKT6 v-SNARE homolog (S. cerevisiae)

IDBP-475967

YKT6 v-SNARE homolog (S. cerevisiae)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:44200968-44214294

Strand

Forward strand

Band

p13

Transcripts

ENST00000223369	ENSP00000223369
ENST00000421621
ENST00000447123
ENST00000424864	ENSP00000412414
ENST00000496112	ENSP00000420805
ENST00000463014
ENST00000478411

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0019706	protein-cysteine S-palmitoyltransferase activity

Biological Process

GO:0006810	transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006903	vesicle targeting
GO:0006904	vesicle docking involved in exocytosis
GO:0008152	metabolic process
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0042147	retrograde transport, endosome to Golgi

Cellular Component

GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0031201	SNARE complex
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000002741

View Gene Order

ENSBTAG00000000274

Not yet available

Pathways

NETPATH

REACTOME

KEGG

hsa04130

SNARE interactions in vesicular transport pathway

INOH

PID NCI

Cross-References

SwissProt

O15498

TrEMBL

A4D2J0 B4DR94 H7C3K7

UniProt Splice Variant

Entrez Gene

10652

UniGene

Hs.520794

RefSeq

NM_006555

HUGO

HGNC:16959

OMIM

606209

CCDS

CCDS5482

HPRD

IMGT

EMBL

AC006454 AK223488 AK299158 AK312622 BC007319 BT007078 CH236960 CH471128 CR456989 CR542008 U95735

GenPept

AAB81131 AAH07319 AAP35741 BAD97208 BAG35508 BAG61206 CAG33270 CAG46805 EAL23763 EAW61111 EAW61112 EAW61113

RNA Seq Atlas

10652