Mus musculus Gene: Pggt1b | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-145118.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | Pggt1b | ||||||||||||||||||
Gene Name | protein geranylgeranyltransferase type I, beta subunit | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||
Ensembl Gene | ENSMUSG00000024477 | ||||||||||||||||||
Encoded Proteins |
protein geranylgeranyltransferase type I, beta subunit
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164219:
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which \'A\' is an aliphatic amino acid and \'X\' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 18:46239949-46280850 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | C | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | Q8BUY9 | ||||||||||||||||||
TrEMBL | Q05BF8 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 225467 | ||||||||||||||||||
UniGene | Mm.262096 Mm.405493 Mm.419521 | ||||||||||||||||||
RefSeq | NM_172627 XM_006525866 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS29230 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
MGI ID | MGI:1917514 | ||||||||||||||||||
MGI Symbol | Pggt1b | ||||||||||||||||||
EMBL | AK081731 BC048404 | ||||||||||||||||||
GenPept | AAH48404 BAC38314 | ||||||||||||||||||
RNA Seq Atlas | 225467 | ||||||||||||||||||