Version 5.4
Mus musculus Gene: Bloc1s5
Summary
InnateDB Gene IDBG-146069.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bloc1s5
Gene Name biogenesis of organelles complex-1, subunit 5, muted
Synonyms 1810074A19Rik; mu; Muted
Species Mus musculus
Ensembl Gene ENSMUSG00000038982
Encoded Proteins
IDBP-146073
muted
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188428:
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:38602709-38635109
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000035899 ENSMUSP00000036614
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008089 anterograde axon cargo transport
GO:0016192 vesicle-mediated transport
GO:0031175 neuron projection development
GO:0032402 melanosome transport
GO:0032474 otolith morphogenesis
GO:0035646 endosome to melanosome transport
GO:0048066 developmental pigmentation
GO:0048490 anterograde synaptic vesicle transport
GO:0050942 positive regulation of pigment cell differentiation
Cellular Component
GO:0030133 transport vesicle
GO:0031083 BLOC-1 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000188428
View Gene Order
ENSBTAG00000039732
Not yet available
Cross-References
SwissProt Q8R015
TrEMBL
UniProt Splice Variant
Entrez Gene 17828
UniGene Mm.261554 Mm.397011
RefSeq NM_139063
OMIM
CCDS CCDS26464
HPRD
IMGT
MGI ID MGI:2178598
MGI Symbol Bloc1s5
EMBL AF426433 AK039050 AK075808 AK147762 AK170614 BC023184 BC024720
GenPept AAH23184 AAH24720 AAL99384 BAC30220 BAC35976 BAE28121 BAE41913
RNA Seq Atlas 17828

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca