Version 5.4
Mus musculus Gene: Rabl6
Summary
InnateDB Gene IDBG-146544.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rabl6
Gene Name RAB, member of RAS oncogene family-like 6
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000015087
Encoded Proteins
IDBP-146546
RIKEN cDNA B230208H17 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196642:
This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:25583018-25608521
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000058137 ENSMUSP00000058746
ENSMUST00000146012
ENSMUST00000150206
ENSMUST00000128942
ENSMUST00000135084
ENSMUST00000143855
ENSMUST00000140778
ENSMUST00000140635
ENSMUST00000140785
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196642
View Gene Order
ENSBTAG00000039573
Not yet available
Cross-References
SwissProt Q5U3K5
TrEMBL
UniProt Splice Variant
Entrez Gene 227624
UniGene Mm.29600 Mm.472627
RefSeq NM_001024616
OMIM
CCDS CCDS38076
HPRD
IMGT
MGI ID MGI:2442633
MGI Symbol Rabl6
EMBL AK045520 AK081440 AK162461 AK171643 AL732590 BC023692 BC058585 BC085507
GenPept AAH23692 AAH58585 AAH85507 BAC32404 BAC38220 BAE36932 BAE42583 CAM25173
RNA Seq Atlas 227624

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca