Version 5.4
Mus musculus Gene: Ddx56
Summary
InnateDB Gene IDBG-146550.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx56
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
Synonyms 2600001H07Rik; D11Ertd619e; Noh61
Species Mus musculus
Ensembl Gene ENSMUSG00000004393
Encoded Proteins
IDBP-146552
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
IDBP-539416
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136271:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:6258919-6267772
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000004507 ENSMUSP00000004507
ENSMUST00000139073
ENSMUST00000151446 ENSMUSP00000122368
ENSMUST00000155874
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 47 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006364 rRNA processing
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136271
View Gene Order
ENSBTAG00000010602
Not yet available
Cross-References
SwissProt
TrEMBL Q5SVX2
UniProt Splice Variant
Entrez Gene 52513
UniGene Mm.29810 Mm.475354
RefSeq NM_026538
OMIM
CCDS CCDS24414
HPRD
IMGT
MGI ID MGI:1277172
MGI Symbol Ddx56
EMBL AL607152
GenPept
RNA Seq Atlas 52513

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca