Version 5.4
Mus musculus Gene: Nedd9
Summary
InnateDB Gene IDBG-146895.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nedd9
Gene Name neural precursor cell expressed, developmentally down-regulated gene 9
Synonyms Cas-L; CasL; HEF1; MEF1; Nedd-9; p105
Species Mus musculus
Ensembl Gene ENSMUSG00000021365
Encoded Proteins
IDBP-146897
neural precursor cell expressed, developmentally down-regulated gene 9
IDBP-620310
neural precursor cell expressed, developmentally down-regulated gene 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111859:
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:41309916-41487320
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000021794 ENSMUSP00000021794
ENSMUST00000163623 ENSMUSP00000125773
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0007155 cell adhesion
GO:0040008 regulation of growth
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005938 cell cortex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111859
View Gene Order
ENSBTAG00000006287
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
NetPath_11
TCR pathway
NetPath_12
BCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.288980 Mm.402665
RefSeq NM_001111324 NM_017464 XM_006516874
OMIM
CCDS CCDS36640 CCDS49247
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca