Version 5.4
Homo sapiens Gene: PRM2
Summary
InnateDB Gene IDBG-14702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRM2
Gene Name protamine 2
Synonyms CT94.2
Species Homo sapiens
Ensembl Gene ENSG00000122304
Encoded Proteins
IDBP-14704
protamine 2
IDBP-368560
protamine 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). See PRM1 (MIM 182880).[supplied by OMIM, Jul 2010]
Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5%% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). See PRM1 (MIM 182880).[supplied by OMIM, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:11275639-11276480
Strand Reverse strand
Band p13.13
Transcripts
ENST00000241808 ENSP00000241808
ENST00000435245 ENSP00000403681
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006323 DNA packaging
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0030261 chromosome condensation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P04554
TrEMBL Q1LZN1
UniProt Splice Variant
Entrez Gene 5620
UniGene
RefSeq NM_001286357 NM_001286359 NM_002762 NM_001286356 NM_001286358
HUGO HGNC:9448
OMIM 182890
CCDS CCDS42118 CCDS66944
HPRD 01691
IMGT
EMBL AB281137 AC009121 AF215713 AK131573 AK292447 AK311798 BC005303 BC042671 BC066338 CH471112 M60332 U15422 X07862 Z46940
GenPept AAA63250 AAC50487 AAF34632 AAH05303 AAH42671 AAH66338 BAD18705 BAF36638 BAF85136 BAG34741 CAA30710 CAA87066 EAW85159
RNA Seq Atlas 5620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca