Version 5.4
Mus musculus Gene: Pdss2
Summary
InnateDB Gene IDBG-148000.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pdss2
Gene Name prenyl (solanesyl) diphosphate synthase, subunit 2
Synonyms 5430420P03Rik; Gm60; kd; mDLP1; Plmp
Species Mus musculus
Ensembl Gene ENSMUSG00000038240
Encoded Proteins
IDBP-148002
prenyl (solanesyl) diphosphate synthase, subunit 2
IDBP-531880
prenyl (solanesyl) diphosphate synthase, subunit 2
IDBP-536389
prenyl (solanesyl) diphosphate synthase, subunit 2
IDBP-536034
prenyl (solanesyl) diphosphate synthase, subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164494:
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:43221486-43464882
Strand Forward strand
Band B2
Transcripts
ENSMUST00000095725 ENSMUSP00000093393
ENSMUST00000160823 ENSMUSP00000124046
ENSMUST00000160108
ENSMUST00000159139 ENSMUSP00000124864
ENSMUST00000162758
ENSMUST00000162008 ENSMUSP00000124440
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000010 trans-hexaprenyltranstransferase activity
GO:0046982 protein heterodimerization activity
GO:0050347 trans-octaprenyltranstransferase activity
Biological Process
GO:0006744 ubiquinone biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0050878 regulation of body fluid levels
GO:0051290 protein heterotetramerization
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164494
View Gene Order
ENSBTAG00000021859
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_196568
Ubiquinol biosynthesis pathway
KEGG
mmu00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160111
Ubiquinol biosynthesis pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q33DR3
TrEMBL
UniProt Splice Variant
Entrez Gene 71365
UniGene Mm.363225 Mm.409693 Mm.413276 Mm.490430
RefSeq NM_027772 XM_006512851 NM_001168289
OMIM
CCDS CCDS35891 CCDS48552
HPRD
IMGT
MGI ID MGI:1918615
MGI Symbol Pdss2
EMBL AB210840 AK017329 AK140091 BC147693 BC147694 BC147752 BC147753
GenPept AAI47694 AAI47695 AAI47753 AAI47754 BAB30693 BAE24234 BAE48218
RNA Seq Atlas 71365

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca