Version 5.4
| Mus musculus Gene: Mnat1 | |||||||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||||||
| InnateDB Gene | IDBG-148230.6 | ||||||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||
| Gene Symbol | Mnat1 | ||||||||||||||||||||||||||
| Gene Name | menage a trois 1 | ||||||||||||||||||||||||||
| Synonyms | E130115E11Rik; MAT1; P36 | ||||||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000021103 | ||||||||||||||||||||||||||
| Encoded Proteins |
menage a trois 1
menage a trois 1
menage a trois 1
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| Protein Structure | |||||||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000020426:
The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
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| Gene Information | |||||||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||||||
| Genomic Location | Chromosome 12:73123717-73273988 | ||||||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||||||
| Band | C3 | ||||||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||||||
| REACTOME |
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
Transcription-coupled NER (TC-NER) pathway
RNA Polymerase I Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Formation of the Early Elongation Complex pathway
G1 Phase pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
Dual incision reaction in GG-NER pathway
RNA Polymerase II Transcription Initiation pathway
Cyclin A:Cdk2-associated events at S phase entry pathway
RNA Polymerase II Promoter Escape pathway
Global Genomic NER (GG-NER) pathway
Formation of incision complex in GG-NER pathway
RNA Polymerase I Transcription Termination pathway
Cell Cycle pathway
Nucleotide Excision Repair pathway
Formation of RNA Pol II elongation complex pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
Cyclin D associated events in G1 pathway
DNA Repair pathway
Mitotic G2-G2/M phases pathway
RNA Polymerase II Transcription Elongation pathway
Cyclin A/B1 associated events during G2/M transition pathway
G1/S Transition pathway
RNA Polymerase II Pre-transcription Events pathway
Mitotic G1-G1/S phases pathway
mRNA Capping pathway
Gene Expression pathway
RNA Polymerase I Promoter Escape pathway
Cyclin E associated events during G1/S transition pathway
Dual incision reaction in TC-NER pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase II Transcription pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
S Phase pathway
RNA Polymerase I Transcription Initiation pathway
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| KEGG |
Basal transcription factors pathway
Nucleotide excision repair pathway
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| INOH |
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
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| PID NCI | |||||||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||
| NETPATH |
AndrogenReceptor pathway
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| REACTOME |
Cyclin A:Cdk2-associated events at S phase entry pathway
Cyclin E associated events during G1/S transition pathway
Cyclin D associated events in G1 pathway
Cyclin A/B1 associated events during G2/M transition pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription Initiation pathway
mRNA Capping pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
Formation of RNA Pol II elongation complex pathway
Formation of the Early Elongation Complex pathway
RNA Polymerase II Transcription Elongation pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
Formation of HIV elongation complex in the absence of HIV Tat pathway
HIV Transcription Initiation pathway
RNA Polymerase II HIV Promoter Escape pathway
Formation of the HIV-1 Early Elongation Complex pathway
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
Tat-mediated elongation of the HIV-1 transcript pathway
RNA Pol II CTD phosphorylation and interaction with CE pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
Formation of transcription-coupled NER (TC-NER) repair complex pathway
Dual incision reaction in TC-NER pathway
Transcription-coupled NER (TC-NER) pathway
Dual incision reaction in GG-NER pathway
Formation of incision complex in GG-NER pathway
G1 Phase pathway
RNA Polymerase I Transcription pathway
Mitotic G1-G1/S phases pathway
S Phase pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
Global Genomic NER (GG-NER) pathway
G1/S Transition pathway
Cell Cycle pathway
HIV Transcription Elongation pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Mitotic G2-G2/M phases pathway
Nucleotide Excision Repair pathway
Gene Expression pathway
Disease pathway
DNA Repair pathway
Negative epigenetic regulation of rRNA expression pathway
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| KEGG |
Basal transcription factors pathway
Nucleotide excision repair pathway
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| INOH |
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
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| PID NCI |
Retinoic acid receptors-mediated signaling
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| Cross-References | |||||||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||||||
| UniGene | |||||||||||||||||||||||||||
| RefSeq | NM_008612 XM_006515526 | ||||||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||||||
| CCDS | CCDS49087 | ||||||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||||||
| MGI ID | |||||||||||||||||||||||||||
| MGI Symbol | |||||||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||||||