Version 5.4
Homo sapiens Gene: PNOC
Summary
InnateDB Gene IDBG-14857.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNOC
Gene Name prepronociceptin
Synonyms PPNOC
Species Homo sapiens
Ensembl Gene ENSG00000168081
Encoded Proteins
IDBP-14859
prepronociceptin
IDBP-477334
prepronociceptin
IDBP-479854
prepronociceptin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:28316986-28343355
Strand Forward strand
Band p21.1
Transcripts
ENST00000301908 ENSP00000301908
ENST00000518479 ENSP00000428059
ENST00000519592
ENST00000522209 ENSP00000430145
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001515 opioid peptide activity
GO:0005184 neuropeptide hormone activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007218 neuropeptide signaling pathway
GO:0007268 synaptic transmission
GO:0007600 sensory perception
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045731
View Gene Order
ENSBTAG00000000534
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.88218
RefSeq NM_001284244 NM_006228
HUGO
OMIM
CCDS CCDS6066 CCDS64862
HPRD 03268
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca