Version 5.4
Mus musculus Gene: Dnajb11
Summary
InnateDB Gene IDBG-148626.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnajb11
Gene Name DnaJ (Hsp40) homolog, subfamily B, member 11
Synonyms 1810031F23Rik; ABBP-2; AL024055; Dj9; ERdj3; ERj3p
Species Mus musculus
Ensembl Gene ENSMUSG00000004460
Encoded Proteins
IDBP-148628
DnaJ (Hsp40) homolog, subfamily B, member 11
IDBP-621353
DnaJ (Hsp40) homolog, subfamily B, member 11
IDBP-706396
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090520:
DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:22857845-22879634
Strand Forward strand
Band B1
Transcripts
ENSMUST00000004574 ENSMUSP00000004574
ENSMUST00000132105
ENSMUST00000133013
ENSMUST00000166487 ENSMUSP00000126828
ENSMUST00000178320 ENSMUSP00000137542
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0016556 mRNA modification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090520
View Gene Order
ENSBTAG00000003151
Not yet available
Pathways
NETPATH
REACTOME
REACT_239697
Unfolded Protein Response (UPR) pathway
REACT_247926
Metabolism of proteins pathway
REACT_231085
IRE1alpha activates chaperones pathway
REACT_106572
XBP1(S) activates chaperone genes pathway
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_17015
Metabolism of proteins pathway
REACT_218371
IRE1alpha activates chaperones pathway
REACT_213782
Metabolism of proteins pathway
REACT_211201
XBP1(S) activates chaperone genes pathway
REACT_226614
Unfolded Protein Response (UPR) pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q99KV1
TrEMBL
UniProt Splice Variant
Entrez Gene 67838
UniGene Mm.37516 Mm.405991 Mm.474374 Mm.477367
RefSeq NM_026400 NM_001190804 NM_001190805
OMIM
CCDS CCDS28070
HPRD
IMGT
MGI ID MGI:1915088
MGI Symbol Dnajb11
EMBL AK050500 AK075785 AK075953 AK148511 AK166730 AY054981 BC003999 BC018282 BC040747 CT027991
GenPept AAH03999 AAH18282 AAH40747 AAL17676 BAC34293 BAC35956 BAC36079 BAE28593 BAE38977 CAO78022
RNA Seq Atlas 67838

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca