Version 5.4
Mus musculus Gene: Anxa8
Summary
InnateDB Gene IDBG-148968.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Anxa8
Gene Name annexin A8
Synonyms AI466995; Anx8
Species Mus musculus
Ensembl Gene ENSMUSG00000021950
Encoded Proteins
IDBP-148970
annexin A8
IDBP-401492
annexin A8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:34085981-34100571
Strand Forward strand
Band B
Transcripts
ENSMUST00000022519 ENSMUSP00000022519
ENSMUST00000120077 ENSMUSP00000113662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0007596 blood coagulation
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000018499
Not yet available
Cross-References
SwissProt
TrEMBL Q921D0
UniProt Splice Variant
Entrez Gene 11752
UniGene Mm.3267
RefSeq NM_001281845 NM_013473
OMIM
CCDS CCDS70565 CCDS26932
HPRD
IMGT
MGI ID MGI:1201374
MGI Symbol Anxa8
EMBL AC164099 BC013271
GenPept AAH13271
RNA Seq Atlas 11752

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca