Version 5.4
Mus musculus Gene: Rbm22
Summary
InnateDB Gene IDBG-149934.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbm22
Gene Name RNA binding motif protein 22
Synonyms 8430430L24Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024604
Encoded Proteins
IDBP-149936
RNA binding motif protein 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086589:
This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:60560736-60572810
Strand Forward strand
Band D3
Transcripts
ENSMUST00000025506 ENSMUSP00000025506
ENSMUST00000160020
ENSMUST00000161544
ENSMUST00000159203
ENSMUST00000160353
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005487 nucleocytoplasmic transporter activity
GO:0008270 zinc ion binding
GO:0017069 snRNA binding
GO:0036002 pre-mRNA binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0033120 positive regulation of RNA splicing
GO:0035690 cellular response to drug
GO:0045292 mRNA cis splicing, via spliceosome
GO:0090316 positive regulation of intracellular protein transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086589
View Gene Order
ENSBTAG00000030366
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt Q8BHS3
TrEMBL
UniProt Splice Variant
Entrez Gene 66810
UniGene Mm.275106 Mm.400830
RefSeq NM_025776
OMIM
CCDS CCDS29272
HPRD
IMGT
MGI ID MGI:1914060
MGI Symbol Rbm22
EMBL AK018452 AK045116 AK150271 AK151758 AK152252 AK166600 AK167509 AK168919 BC080205
GenPept AAH80205 BAB31220 BAC32229 BAE29427 BAE30665 BAE31073 BAE38885 BAE39585 BAE40732
RNA Seq Atlas 66810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca