Version 5.4
Mus musculus Gene: Wapal
Summary
InnateDB Gene IDBG-150449.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wapal
Gene Name wings apart-like homolog (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041408
Encoded Proteins
IDBP-150451
wings apart-like homolog (Drosophila)
IDBP-150453
wings apart-like homolog (Drosophila)
IDBP-532407
wings apart-like homolog (Drosophila)
IDBP-625033
wings apart-like homolog (Drosophila)
IDBP-625035
wings apart-like homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000062650:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:34673928-34747983
Strand Forward strand
Band B
Transcripts
ENSMUST00000048263 ENSMUSP00000040232
ENSMUST00000090027 ENSMUSP00000087481
ENSMUST00000111895
ENSMUST00000151285 ENSMUSP00000117282
ENSMUST00000172658
ENSMUST00000174559 ENSMUSP00000133779
ENSMUST00000169910 ENSMUSP00000130547
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0008156 negative regulation of DNA replication
GO:0009636 response to toxic substance
GO:0035562 negative regulation of chromatin binding
GO:0045875 negative regulation of sister chromatid cohesion
GO:0048146 positive regulation of fibroblast proliferation
GO:0051983 regulation of chromosome segregation
GO:0060623 regulation of chromosome condensation
GO:0071168 protein localization to chromatin
GO:0071922 regulation of cohesin localization to chromatin
Cellular Component
GO:0000785 chromatin
GO:0000795 synaptonemal complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008278 cohesin complex
GO:0015630 microtubule cytoskeleton
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000062650
View Gene Order
ENSBTAG00000012213
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_250427
Mitotic Telophase/Cytokinesis pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_196634
Cohesin Loading onto Chromatin pathway
REACT_196614
Establishment of Sister Chromatid Cohesion pathway
REACT_202512
Mitotic Anaphase pathway
REACT_253623
S Phase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_150421
Cohesin Loading onto Chromatin pathway
REACT_1932
Mitotic Telophase/Cytokinesis pathway
REACT_150266
Establishment of Sister Chromatid Cohesion pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27957 Mm.489820
RefSeq NM_001004436 XM_006518823
OMIM
CCDS CCDS36880
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca