InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ckm

Summary

InnateDB Gene

IDBG-150644.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ckm

Gene Name

creatine kinase, muscle

Synonyms

Ckmm; M-CK; MCK

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030399

Encoded Proteins

IDBP-150646

creatine kinase, muscle

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104879:
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:19411094-19421583

Strand

Forward strand

Band

Transcripts

ENSMUST00000003643

ENSMUSP00000003643

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	10 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004111	creatine kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups