Version 5.4
Mus musculus Gene: Slc6a7
Summary
InnateDB Gene IDBG-150702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc6a7
Gene Name solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052026
Encoded Proteins
IDBP-150704
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000011083:
This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:60995381-61014199
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000025520 ENSMUSP00000025520
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006836 neurotransmitter transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000011083
View Gene Order
ENSBTAG00000000910
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_253228
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20506
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_813
Creatine metabolism pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6PGE7
TrEMBL
UniProt Splice Variant
Entrez Gene 240332
UniGene Mm.39846
RefSeq NM_201353 XM_006525929 XM_006525930 XM_006525931 XM_006525934
OMIM
CCDS CCDS29278
HPRD
IMGT
MGI ID MGI:2147363
MGI Symbol Slc6a7
EMBL BC050103 BC057070
GenPept AAH50103 AAH57070
RNA Seq Atlas 240332

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca