Version 5.4
Mus musculus Gene: Gemin7
Summary
InnateDB Gene IDBG-151134.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gemin7
Gene Name gem (nuclear organelle) associated protein 7
Synonyms 2400008I04Rik; AI120175; AI461688
Species Mus musculus
Ensembl Gene ENSMUSG00000044709
Encoded Proteins
IDBP-151136
gem (nuclear organelle) associated protein 7
IDBP-401443
gem (nuclear organelle) associated protein 7
IDBP-401440
gem (nuclear organelle) associated protein 7
IDBP-401442
gem (nuclear organelle) associated protein 7
IDBP-401441
gem (nuclear organelle) associated protein 7
IDBP-535506
gem (nuclear organelle) associated protein 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142252:
The protein encoded by this gene is a component of the core SMN complex, which is required for pre-mRNA splicing in the nucleus. The encoded protein is found in the nucleoplasm, in nuclear "gems" (Gemini of Cajal bodies), and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:19564946-19573823
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000051364 ENSMUSP00000055844
ENSMUST00000117222 ENSMUSP00000113266
ENSMUST00000122127 ENSMUSP00000113709
ENSMUST00000122055 ENSMUSP00000113583
ENSMUST00000119912 ENSMUSP00000112742
ENSMUST00000151646 ENSMUSP00000116207
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000387 spliceosomal snRNP assembly
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016604 nuclear body
GO:0032797 SMN complex
GO:0034719 SMN-Sm protein complex
GO:0097504 Gemini of coiled bodies
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000142252
View Gene Order
ENSBTAG00000010668
Not yet available
Pathways
NETPATH
REACTOME
REACT_224866
Metabolism of non-coding RNA pathway
REACT_206812
snRNP Assembly pathway
REACT_233572
Gene Expression pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11066
snRNP Assembly pathway
REACT_11052
Metabolism of non-coding RNA pathway
REACT_71
Gene Expression pathway
REACT_226022
Gene Expression pathway
REACT_206124
Metabolism of non-coding RNA pathway
REACT_224480
snRNP Assembly pathway
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt Q9CWY4
TrEMBL D3Z684
UniProt Splice Variant
Entrez Gene 69731
UniGene
RefSeq NM_027189
OMIM
CCDS CCDS20907
HPRD
IMGT
MGI ID MGI:1916981
MGI Symbol Gemin7
EMBL AC149052 AK010303 BC028527
GenPept AAH28527 BAB26836
RNA Seq Atlas 69731

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca