Version 5.4
Mus musculus Gene: Mat1a
Summary
InnateDB Gene IDBG-151663.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mat1a
Gene Name methionine adenosyltransferase I, alpha
Synonyms AdoMet; AI046368; Ams; MAT; MATA1; SAMS; SAMS1
Species Mus musculus
Ensembl Gene ENSMUSG00000037798
Encoded Proteins
IDBP-151665
methionine adenosyltransferase I, alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the AdoMet synthase family. Methionine adenosyltransferase is a product of this gene (the alpha form) and the beta form and catalyzes the formation of S-adenosylmethionine from methionine and ATP.[provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:41105381-41124412
Strand Forward strand
Band B
Transcripts
ENSMUST00000047286 ENSMUSP00000044288
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004478 methionine adenosyltransferase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0006730 one-carbon metabolic process
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151224
View Gene Order
ENSBTAG00000005963
Not yet available
Pathways
NETPATH
REACTOME
REACT_243247
Phase II conjugation pathway
REACT_188937
Metabolism pathway
REACT_241023
Methylation pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_202492
Sulfur amino acid metabolism pathway
REACT_232343
Biological oxidations pathway
KEGG
mmu00270
Cysteine and methionine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115639
Sulfur amino acid metabolism pathway
REACT_6946
Methylation pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
hsa00270
Cysteine and methionine metabolism pathway
INOH
INOH website
Methionine Cysteine metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.14064
RefSeq NM_133653 XM_006518450
OMIM
CCDS CCDS26959
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca