Version 5.4
Homo sapiens Gene: CSNK1G2
Summary
InnateDB Gene IDBG-15174.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSNK1G2
Gene Name casein kinase 1, gamma 2
Synonyms CK1g2
Species Homo sapiens
Ensembl Gene ENSG00000133275
Encoded Proteins
IDBP-15176
casein kinase 1, gamma 2
IDBP-810572
casein kinase 1, gamma 2
IDBP-810584
casein kinase 1, gamma 2
IDBP-760475
IDBP-763756
IDBP-761640
IDBP-810571
casein kinase 1, gamma 2
IDBP-810583
casein kinase 1, gamma 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1941149-1981338
Strand Forward strand
Band p13.3
Transcripts
ENST00000255641 ENSP00000255641
ENST00000585959 ENSP00000480185
ENST00000589861
ENST00000585957 ENSP00000480052
ENST00000589350 ENSP00000465106
ENST00000589385 ENSP00000468637
ENST00000590106
ENST00000591752 ENSP00000467214
ENST00000591002 ENSP00000480929
ENST00000614707
ENST00000615564 ENSP00000482716
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0001948 glycoprotein binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0042277 peptide binding
GO:0051219 phosphoprotein binding
Biological Process
GO:0006468 protein phosphorylation
GO:0006665 sphingolipid metabolic process
GO:0007165 signal transduction
GO:0016055 Wnt signaling pathway
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003345
View Gene Order
ENSBTAG00000016797
Not yet available
Pathways
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_228096
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
REACT_228331
Signaling by WNT in cancer pathway
REACT_11045
Signaling by Wnt pathway
REACT_200610
disassembly of the destruction complex and recruitment of AXIN to the membrane pathway
REACT_111102
Signal Transduction pathway
REACT_200777
TCF dependent signaling in response to WNT pathway
REACT_228188
RNF mutants show enhanced WNT signaling and proliferation pathway
REACT_111217
Metabolism pathway
REACT_228279
XAV939 inhibits tankyrase, stabilizing AXIN pathway
REACT_116125
Disease pathway
KEGG
hsa04340
Hedgehog signaling pathway pathway
INOH
INOH website
IL-7 signaling pathway
INOH website
JAK STAT pathway and regulation pathway
INOH website
EPO signaling pathway pathway
INOH website
VEGF signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 1455
UniGene
RefSeq NM_001319
HUGO HGNC:2455
OMIM 602214
CCDS CCDS12077
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 1455

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca