Version 5.4
Mus musculus Gene: Pigh
Summary
InnateDB Gene IDBG-152582.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigh
Gene Name phosphatidylinositol glycan anchor biosynthesis, class H
Synonyms 2210416H01Rik; A930028P05Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000021120
Encoded Proteins
IDBP-152584
phosphatidylinositol glycan anchor biosynthesis, class H
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100564:
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:79080673-79089670
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000072154 ENSMUSP00000072018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
GO:0008150 biological_process
Cellular Component
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005730 nucleolus
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100564
View Gene Order
ENSBTAG00000018299
Not yet available
Pathways
NETPATH
REACTOME
REACT_244576
Post-translational modification: synthesis of GPI-anchored proteins pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_243945
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
mmu00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_952
Synthesis of glycosylphosphatidylinositol (GPI) pathway
REACT_1853
Post-translational modification: synthesis of GPI-anchored proteins pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q5M9N4
TrEMBL
UniProt Splice Variant
Entrez Gene 110417
UniGene Mm.268317
RefSeq NM_029988
OMIM
CCDS CCDS26006
HPRD
IMGT
MGI ID MGI:99463
MGI Symbol Pigh
EMBL AK167892 BC086806
GenPept AAH86806 BAE39904
RNA Seq Atlas 110417

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca