Version 5.4
Mus musculus Gene: Atoh1
Summary
InnateDB Gene IDBG-152860.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atoh1
Gene Name atonal homolog 1 (Drosophila)
Synonyms bHLHa14; Hath1; MATH-1; Math1
Species Mus musculus
Ensembl Gene ENSMUSG00000073043
Encoded Proteins
IDBP-152862
atonal homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172238:
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:64729146-64731233
Strand Forward strand
Band C1
Transcripts
ENSMUST00000101351 ENSMUSP00000098903
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001764 neuron migration
GO:0006351 transcription, DNA-templated
GO:0007411 axon guidance
GO:0007420 brain development
GO:0021987 cerebral cortex development
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0042472 inner ear morphogenesis
GO:0042491 auditory receptor cell differentiation
GO:0042667 auditory receptor cell fate specification
GO:0042668 auditory receptor cell fate determination
GO:0043066 negative regulation of apoptotic process
GO:0045609 positive regulation of auditory receptor cell differentiation
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048839 inner ear development
GO:2000982 positive regulation of inner ear receptor cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172238
View Gene Order
ENSBTAG00000002895
Not yet available
Cross-References
SwissProt P48985
TrEMBL
UniProt Splice Variant
Entrez Gene 11921
UniGene Mm.57229
RefSeq NM_007500
OMIM
CCDS CCDS20203
HPRD
IMGT
MGI ID MGI:104654
MGI Symbol Atoh1
EMBL BC010820 BC051256 D43694
GenPept AAH10820 AAH51256 BAA07791
RNA Seq Atlas 11921

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca