Version 5.4
Mus musculus Gene: Commd1
Summary
InnateDB Gene IDBG-154032.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Commd1
Gene Name COMM domain containing 1
Synonyms AI256843; Murr1; U2/Mu
Species Mus musculus
Ensembl Gene ENSMUSG00000051355
Encoded Proteins
IDBP-154034
COMM domain containing 1
IDBP-154036
COMM domain containing 1
IDBP-154038
COMM domain containing 1
IDBP-541047
COMM domain containing 1
IDBP-536216
COMM domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173163:
COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]).[supplied by OMIM, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:22896136-22982382
Strand Reverse strand
Band A3.2
Transcripts
ENSMUST00000071068 ENSMUSP00000065079
ENSMUST00000057843 ENSMUSP00000053606
ENSMUST00000093270 ENSMUSP00000090958
ENSMUST00000160826 ENSMUSP00000125609
ENSMUST00000159081 ENSMUSP00000124719
ENSMUST00000161944
ENSMUST00000162924
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 51 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
Biological Process
GO:0006878 cellular copper ion homeostasis
GO:0031398 positive regulation of protein ubiquitination
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0055070 copper ion homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031462 Cul2-RING ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173163
View Gene Order
ENSBTAG00000019867
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.259903 Mm.395495 Mm.416828 Mm.490500
RefSeq NM_144514
OMIM
CCDS CCDS24472
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca