InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cct4

Summary

InnateDB Gene

IDBG-154117.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cct4

Gene Name

chaperonin containing Tcp1, subunit 4 (delta)

Synonyms

2610204B21Rik; A45; C78323; Cctd

Species

Mus musculus

Ensembl Gene

ENSMUSG00000007739

Encoded Proteins

IDBP-154119

chaperonin containing Tcp1, subunit 4 (delta)

IDBP-627367

chaperonin containing Tcp1, subunit 4 (delta)

IDBP-627368

chaperonin containing Tcp1, subunit 4 (delta)

IDBP-627369

chaperonin containing Tcp1, subunit 4 (delta)

IDBP-627370

chaperonin containing Tcp1, subunit 4 (delta)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115484:
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:22990519-23003780

Strand

Forward strand

Band

A3.2

Transcripts

ENSMUST00000020562	ENSMUSP00000020562
ENSMUST00000145912
ENSMUST00000173867	ENSMUSP00000133523
ENSMUST00000173853	ENSMUSP00000133677
ENSMUST00000174244
ENSMUST00000174047	ENSMUSP00000134248
ENSMUST00000174659	ENSMUSP00000133667
ENSMUST00000174746
ENSMUST00000174689

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	79 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding
GO:0051082	unfolded protein binding

Biological Process

GO:0006457	protein folding
GO:0007339	binding of sperm to zona pellucida
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0002199	zona pellucida receptor complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005832	chaperonin-containing T-complex
GO:0005874	microtubule
GO:0042470	melanosome
GO:0044297	cell body
GO:0070062	extracellular vesicular exosome