Version 5.4
Mus musculus Gene: Wdr34
Summary
InnateDB Gene IDBG-155156.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr34
Gene Name WD repeat domain 34
Synonyms 3200002I06Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000039715
Encoded Proteins
IDBP-253336
WD repeat domain 34
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 19521662
[Homo sapiens] WDR34 is a MAP3K7 (TAK1)-associated inhibitor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119333:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:30031546-30048881
Strand Reverse strand
Band B
Transcripts
ENSMUST00000113711 ENSMUSP00000109340
ENSMUST00000139145
ENSMUST00000143892
ENSMUST00000146275
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005814 centriole
GO:0005930 axoneme
GO:0036064 ciliary basal body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119333
View Gene Order
ENSBTAG00000015343
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.88053
RefSeq NM_001008498
OMIM
CCDS CCDS15865
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca