Mus musculus Gene: Tbata | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-155198.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | Tbata | ||||||||||||||||||
Gene Name | thymus, brain and testes associated | ||||||||||||||||||
Synonyms | 1700021K02Rik; AI428928; Spatial; Titest | ||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||
Ensembl Gene | ENSMUSG00000020096 | ||||||||||||||||||
Encoded Proteins |
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a putative transcription factor that is highly expressed in thymic cortical stromal cells, and may be involved in T-cell development. Its expression is developmentally regulated in the testis, where it is restricted to the haploid round spermatids during spermatogenesis, and thus this gene may also have a role in the control of male germ cell development. Alternative splicing of this gene results in two sets of transcript variants: the variants containing 5 additional exons at the 3' end encode long isoforms that are highly expressed in the testis, while the variants lacking the 3' end exons encode short isoforms that are highly expressed in the thymus. Most of the transcripts encoding the short isoforms have been shown to initiate translation from non-AUG (CUG) start sites. [provided by RefSeq, Jul 2008] This gene encodes a putative transcription factor that is highly expressed in thymic cortical stromal cells, and may be involved in T-cell development. Its expression is developmentally regulated in the testis, where it is restricted to the haploid round spermatids during spermatogenesis, and thus this gene may also have a role in the control of male germ cell development. Alternative splicing of this gene results in two sets of transcript variants: the variants containing 5 additional exons at the 3\' end encode long isoforms that are highly expressed in the testis, while the variants lacking the 3\' end exons encode short isoforms that are highly expressed in the thymus. Most of the transcripts encoding the short isoforms have been shown to initiate translation from non-AUG (CUG) start sites. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 10:61171954-61188841 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | B4 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | Q7TSD4 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 65971 | ||||||||||||||||||
UniGene | Mm.30227 | ||||||||||||||||||
RefSeq | NM_001017433 NM_001017407 NM_001017409 NM_001017419 NM_001017441 NM_023064 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS23873 CCDS23874 CCDS48572 CCDS48573 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
MGI ID | MGI:1923820 | ||||||||||||||||||
MGI Symbol | Tbata | ||||||||||||||||||
EMBL | AF257502 AF257503 AF521591 AF521592 AK038284 AY243457 AY243458 AY243459 EU622858 | ||||||||||||||||||
GenPept | AAG37103 AAG37104 AAP41210 AAP41211 AAP41212 AAP50907 AAP50908 ACD01420 BAC29958 | ||||||||||||||||||
RNA Seq Atlas | 65971 | ||||||||||||||||||