Mus musculus Gene: Tbata
Summary
InnateDB Gene IDBG-155198.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbata
Gene Name thymus, brain and testes associated
Synonyms 1700021K02Rik; AI428928; Spatial; Titest
Species Mus musculus
Ensembl Gene ENSMUSG00000020096
Encoded Proteins
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
thymus, brain and testes associated
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a putative transcription factor that is highly expressed in thymic cortical stromal cells, and may be involved in T-cell development. Its expression is developmentally regulated in the testis, where it is restricted to the haploid round spermatids during spermatogenesis, and thus this gene may also have a role in the control of male germ cell development. Alternative splicing of this gene results in two sets of transcript variants: the variants containing 5 additional exons at the 3' end encode long isoforms that are highly expressed in the testis, while the variants lacking the 3' end exons encode short isoforms that are highly expressed in the thymus. Most of the transcripts encoding the short isoforms have been shown to initiate translation from non-AUG (CUG) start sites. [provided by RefSeq, Jul 2008]
This gene encodes a putative transcription factor that is highly expressed in thymic cortical stromal cells, and may be involved in T-cell development. Its expression is developmentally regulated in the testis, where it is restricted to the haploid round spermatids during spermatogenesis, and thus this gene may also have a role in the control of male germ cell development. Alternative splicing of this gene results in two sets of transcript variants: the variants containing 5 additional exons at the 3\' end encode long isoforms that are highly expressed in the testis, while the variants lacking the 3\' end exons encode short isoforms that are highly expressed in the thymus. Most of the transcripts encoding the short isoforms have been shown to initiate translation from non-AUG (CUG) start sites. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:61171954-61188841
Strand Forward strand
Band B4
Transcripts
ENSMUST00000035894 ENSMUSP00000036422
ENSMUST00000079235 ENSMUSP00000078227
ENSMUST00000122261 ENSMUSP00000113902
ENSMUST00000121297 ENSMUSP00000113253
ENSMUST00000131879 ENSMUSP00000118942
ENSMUST00000143207
ENSMUST00000148181
ENSMUST00000151886
ENSMUST00000140456
ENSMUST00000126831 ENSMUSP00000119957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0048515 spermatid differentiation
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q7TSD4
TrEMBL
UniProt Splice Variant
Entrez Gene 65971
UniGene Mm.30227
RefSeq NM_001017433 NM_001017407 NM_001017409 NM_001017419 NM_001017441 NM_023064
OMIM
CCDS CCDS23873 CCDS23874 CCDS48572 CCDS48573
HPRD
IMGT
MGI ID MGI:1923820
MGI Symbol Tbata
EMBL AF257502 AF257503 AF521591 AF521592 AK038284 AY243457 AY243458 AY243459 EU622858
GenPept AAG37103 AAG37104 AAP41210 AAP41211 AAP41212 AAP50907 AAP50908 ACD01420 BAC29958
RNA Seq Atlas 65971