InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Fabp1

Summary

InnateDB Gene

IDBG-155319.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fabp1

Gene Name

fatty acid binding protein 1, liver

Synonyms

Fabpl; L-FABP

Species

Mus musculus

Ensembl Gene

ENSMUSG00000054422

Encoded Proteins

IDBP-155321

fatty acid binding protein 1, liver

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163586:
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:71199827-71205023

Strand

Forward strand

Band

Transcripts

ENSMUST00000067492

ENSMUSP00000064655

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005324	long-chain fatty acid transporter activity
GO:0005504	fatty acid binding
GO:0005515	protein binding
GO:0005543	phospholipid binding
GO:0008144	drug binding
GO:0016209	antioxidant activity
GO:0032052	bile acid binding

Biological Process

GO:0006810	transport
GO:0008284	positive regulation of cell proliferation
GO:0015909	long-chain fatty acid transport
GO:0032000	positive regulation of fatty acid beta-oxidation
GO:0043066	negative regulation of apoptotic process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050892	intestinal absorption
GO:0051345	positive regulation of hydrolase activity
GO:0070301	cellular response to hydrogen peroxide
GO:0071456	cellular response to hypoxia