Version 5.4
Mus musculus Gene: Satb2
Summary
InnateDB Gene IDBG-155567.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Satb2
Gene Name special AT-rich sequence binding protein 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038331
Encoded Proteins
IDBP-155569
special AT-rich sequence binding protein 2
IDBP-251810
special AT-rich sequence binding protein 2
IDBP-716056
IDBP-715060
IDBP-714100
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119042:
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:56793981-56978650
Strand Reverse strand
Band C1.3
Transcripts
ENSMUST00000042857 ENSMUSP00000046067
ENSMUST00000114415 ENSMUSP00000110057
ENSMUST00000177424 ENSMUSP00000135391
ENSMUST00000176759 ENSMUSP00000135163
ENSMUST00000177282 ENSMUSP00000135542
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001764 neuron migration
GO:0002076 osteoblast development
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009880 embryonic pattern specification
GO:0010468 regulation of gene expression
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048704 embryonic skeletal system morphogenesis
GO:0051216 cartilage development
GO:0060021 palate development
GO:0071310 cellular response to organic substance
Cellular Component
GO:0000118 histone deacetylase complex
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119042
View Gene Order
ENSBTAG00000016334
Not yet available
Cross-References
SwissProt Q8VI24
TrEMBL H3BKV4 Q546B3
UniProt Splice Variant
Entrez Gene 212712
UniGene Mm.145599 Mm.399699
RefSeq NM_139146 XM_006495826 XM_006495827
OMIM
CCDS CCDS14965
HPRD
IMGT
MGI ID MGI:2679336
MGI Symbol Satb2
EMBL AC101777 AC131072 AF319623 AJ606045 AK129270 BC138625 BC138626 CH466548
GenPept AAI38626 AAI38627 AAL37172 BAC98080 CAE54289 EDL00043
RNA Seq Atlas 212712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca