Version 5.4
Mus musculus Gene: Glra3
Summary
InnateDB Gene IDBG-155891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Glra3
Gene Name glycine receptor, alpha 3 subunit
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038257
Encoded Proteins
IDBP-155893
glycine receptor, alpha 3 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145451:
The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 [PubMed 7894176]).[supplied by OMIM, Nov 2009]
This gene encodes a member of the ligand-gated ion channel protein family. The encoded protein is a member of the glycine receptor subfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:55940460-56125429
Strand Forward strand
Band B2
Transcripts
ENSMUST00000000275 ENSMUSP00000000275
ENSMUST00000164020
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
GO:0016594 glycine binding
GO:0016934 extracellular-glycine-gated chloride channel activity
GO:0022824 transmitter-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0034707 chloride channel complex
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145451
View Gene Order
ENSBTAG00000019732
Not yet available
Pathways
NETPATH
REACTOME
REACT_198558
Ligand-gated ion channel transport pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt Q91XP5
TrEMBL G5E811 Q9JL29
UniProt Splice Variant
Entrez Gene 110304
UniGene Mm.307061
RefSeq NM_080438
OMIM
CCDS CCDS40340
HPRD
IMGT
MGI ID MGI:95749
MGI Symbol Glra3
EMBL AC117729 AC119900 AF214575 AF362764 AY230204 CH466569
GenPept AAF34619 AAK51962 AAP22967 EDL28601
RNA Seq Atlas 110304

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca