Version 5.4
Mus musculus Gene: Mpp1
Summary
InnateDB Gene IDBG-156946.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mpp1
Gene Name membrane protein, palmitoylated
Synonyms 55kDa; C130070C03Rik; p55
Species Mus musculus
Ensembl Gene ENSMUSG00000031402
Encoded Proteins
IDBP-156948
membrane protein, palmitoylated
IDBP-252490
membrane protein, palmitoylated
IDBP-252492
membrane protein, palmitoylated
IDBP-537434
membrane protein, palmitoylated
IDBP-537184
membrane protein, palmitoylated
IDBP-533338
membrane protein, palmitoylated
IDBP-535321
membrane protein, palmitoylated
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130830:
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:75109733-75131016
Strand Reverse strand
Band A7.3
Transcripts
ENSMUST00000033775 ENSMUSP00000033775
ENSMUST00000114092 ENSMUSP00000109726
ENSMUST00000114091 ENSMUSP00000109725
ENSMUST00000132501 ENSMUSP00000118693
ENSMUST00000132935
ENSMUST00000135285
ENSMUST00000153318 ENSMUSP00000116897
ENSMUST00000155742 ENSMUSP00000116401
ENSMUST00000156975
ENSMUST00000127023 ENSMUSP00000117003
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0090022 regulation of neutrophil chemotaxis
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0030863 cortical cytoskeleton
GO:0032420 stereocilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000130830
View Gene Order
ENSBTAG00000013046
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.391267
RefSeq NM_008621
OMIM
CCDS CCDS30236
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca