Version 5.4
Mus musculus Gene: Rps10
Summary
InnateDB Gene IDBG-156995.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rps10
Gene Name ribosomal protein S10
Synonyms 2210402A09Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000052146
Encoded Proteins
IDBP-156997
ribosomal protein S10
IDBP-250831
ribosomal protein S10
IDBP-250833
ribosomal protein S10
IDBP-714155
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124614:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:27630422-27636629
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000025052 ENSMUSP00000025052
ENSMUST00000114882 ENSMUSP00000110532
ENSMUST00000114881 ENSMUSP00000110531
ENSMUST00000155071
ENSMUST00000150763
ENSMUST00000145226
ENSMUST00000152982
ENSMUST00000178774 ENSMUSP00000136042
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 79 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
Cellular Component
GO:0005730 nucleolus
GO:0022627 cytosolic small ribosomal subunit
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124614
View Gene Order
ENSBTAG00000015598
Not yet available
Pathways
NETPATH
REACTOME
REACT_253640
Peptide chain elongation pathway
REACT_255163
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
REACT_254308
Translation pathway
REACT_231519
Eukaryotic Translation Termination pathway
REACT_256488
Translation initiation complex formation pathway
REACT_198522
Nonsense-Mediated Decay (NMD) pathway
REACT_247926
Metabolism of proteins pathway
REACT_198528
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_198524
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_229570
Cap-dependent Translation Initiation pathway
REACT_262064
Eukaryotic Translation Initiation pathway
REACT_196445
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_232254
Eukaryotic Translation Elongation pathway
REACT_249044
Formation of a pool of free 40S subunits pathway
REACT_233572
Gene Expression pathway
REACT_259469
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_236458
Ribosomal scanning and start codon recognition pathway
REACT_262078
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_249316
Formation of the ternary complex, and subsequently, the 43S complex pathway
KEGG
mmu03010
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_79
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_75768
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_75822
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_2085
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_1979
Translation initiation complex formation pathway
REACT_1258
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
REACT_1797
Formation of a pool of free 40S subunits pathway
REACT_1079
Formation of the ternary complex, and subsequently, the 43S complex pathway
REACT_931
Ribosomal scanning and start codon recognition pathway
REACT_1986
Eukaryotic Translation Termination pathway
REACT_1404
Peptide chain elongation pathway
REACT_1477
Eukaryotic Translation Elongation pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_9491
Viral mRNA Translation pathway
REACT_2159
Eukaryotic Translation Initiation pathway
REACT_6167
Influenza Infection pathway
REACT_75886
Nonsense-Mediated Decay (NMD) pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_2099
Cap-dependent Translation Initiation pathway
REACT_6145
Influenza Life Cycle pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
REACT_221721
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_203882
Formation of the ternary complex, and subsequently, the 43S complex pathway
REACT_246268
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_202833
Peptide chain elongation pathway
REACT_225310
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_226022
Gene Expression pathway
REACT_218564
Eukaryotic Translation Initiation pathway
REACT_225918
Cap-dependent Translation Initiation pathway
REACT_222208
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_216229
Formation of a pool of free 40S subunits pathway
REACT_209048
Translation pathway
REACT_202903
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_213782
Metabolism of proteins pathway
REACT_220444
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
REACT_224343
Translation initiation complex formation pathway
REACT_222777
Nonsense-Mediated Decay (NMD) pathway
REACT_222420
Ribosomal scanning and start codon recognition pathway
REACT_201931
Eukaryotic Translation Termination pathway
REACT_225811
Eukaryotic Translation Elongation pathway
KEGG
hsa03010
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_025963 XM_006524818 XM_006536781
OMIM
CCDS CCDS37522
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca