Mus musculus Gene: Taf11 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-157327.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Taf11 | ||||||||||||||||||||||
Gene Name | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor | ||||||||||||||||||||||
Synonyms | 1110038O14Rik; 28kDa; AI115401; AL024207; AW552398; PRO214; TAF2I; TAFII28 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000024218 | ||||||||||||||||||||||
Encoded Proteins |
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064995:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 17:27901122-27909242 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | A3.3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
Gene Expression pathway
RNA Polymerase II Transcription pathway
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KEGG |
Basal transcription factors pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
HIV Transcription Initiation pathway
RNA Polymerase II HIV Promoter Escape pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
HIV Infection pathway
Gene Expression pathway
Disease pathway
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KEGG |
Basal transcription factors pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.267998 | ||||||||||||||||||||||
RefSeq | NM_026836 XM_006524861 XM_006536784 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS28571 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||