Version 5.4
Mus musculus Gene: Ddx60
Summary
InnateDB Gene IDBG-157673.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx60
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037921
Encoded Proteins
IDBP-157675
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
IDBP-157677
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
IDBP-539288
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
IDBP-537000
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137628:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:61928087-62037701
Strand Forward strand
Band B3.1
Transcripts
ENSMUST00000093485 ENSMUSP00000091197
ENSMUST00000070631 ENSMUSP00000070741
ENSMUST00000154398 ENSMUSP00000122841
ENSMUST00000156980 ENSMUSP00000120424
ENSMUST00000153806
ENSMUST00000136121
ENSMUST00000155209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0008152 metabolic process
GO:0009615 response to virus
GO:0051607 defense response to virus
GO:1900245 positive regulation of MDA-5 signaling pathway
GO:1900246 positive regulation of RIG-I signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000137628
View Gene Order
Cross-References
SwissProt
TrEMBL D3YZ76 D3Z3B3
UniProt Splice Variant
Entrez Gene 234311
UniGene Mm.275233
RefSeq NM_001081215 XM_006509392 XM_006509394 XM_006509395 XM_006509396
OMIM
CCDS CCDS52556
HPRD
IMGT
MGI ID MGI:2384570
MGI Symbol Ddx60
EMBL AC139846 AC144858
GenPept
RNA Seq Atlas 234311

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca