Version 5.4
Mus musculus Gene: Arcn1
Summary
InnateDB Gene IDBG-158210.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arcn1
Gene Name archain 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032096
Encoded Proteins
IDBP-158212
archain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095139:
This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:44741564-44767845
Strand Reverse strand
Band A5.2
Transcripts
ENSMUST00000034607 ENSMUSP00000034607
ENSMUST00000150160
ENSMUST00000125164
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0008344 adult locomotory behavior
GO:0016192 vesicle-mediated transport
GO:0021691 cerebellar Purkinje cell layer maturation
GO:0043473 pigmentation
GO:0048193 Golgi vesicle transport
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0030126 COPI vesicle coat
GO:0030131 clathrin adaptor complex
GO:0030137 COPI-coated vesicle
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000095139
View Gene Order
ENSBTAG00000006690
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_207127
Golgi to ER Retrograde Transport pathway
REACT_227904
COPI Mediated Transport pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11096
COPI Mediated Transport pathway
REACT_11208
Golgi to ER Retrograde Transport pathway
REACT_11123
Membrane Trafficking pathway
REACT_211733
Golgi to ER Retrograde Transport pathway
REACT_206224
COPI Mediated Transport pathway
REACT_213260
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q5XJY5
TrEMBL Q3TDU1 Q8R1S6
UniProt Splice Variant
Entrez Gene 213827
UniGene Mm.371682 Mm.402278 Mm.465568 Mm.476822
RefSeq NM_145985
OMIM
CCDS CCDS40602
HPRD
IMGT
MGI ID MGI:2387591
MGI Symbol Arcn1
EMBL AK028556 AK170005 BC017124 BC023728 BC024127 BC033387 BC034754 BC083152 CH466522
GenPept AAH17124 AAH23728 AAH24127 AAH33387 AAH34754 AAH83152 BAC26007 BAE41508 EDL25614
RNA Seq Atlas 213827

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca