Version 5.4
Mus musculus Gene: Klhl2
Summary
InnateDB Gene IDBG-158358.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhl2
Gene Name kelch-like 2, Mayven (Drosophila)
Synonyms 6030411N21Rik; ABP-KELCH; AU020744; Mav
Species Mus musculus
Ensembl Gene ENSMUSG00000031605
Encoded Proteins
IDBP-158360
kelch-like 2, Mayven (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109466:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:64739863-64849818
Strand Reverse strand
Band B3.1
Transcripts
ENSMUST00000034017 ENSMUSP00000034017
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0001725 stress fiber
GO:0001726 ruffle
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0031463 Cul3-RING ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000109466
View Gene Order
ENSBTAG00000005263
Not yet available
Cross-References
SwissProt Q8JZP3
TrEMBL
UniProt Splice Variant
Entrez Gene 77113
UniGene Mm.395662 Mm.490416
RefSeq NM_178633
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:1924363
MGI Symbol Klhl2
EMBL AK032116 BC024572 BC031142 BC031144
GenPept AAH24572 AAH31142 AAH31144 BAC27712
RNA Seq Atlas 77113

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca