Mus musculus Gene: Sumo1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-158495.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Sumo1 | ||||||||||||||||||||||
Gene Name | SMT3 suppressor of mif two 3 homolog 1 (yeast) | ||||||||||||||||||||||
Synonyms | GMP1; PIC1; SENTRIN; SMT3; Smt3C; SMT3H3; SMTP3; SUMO-1; Ubl1 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000026021 | ||||||||||||||||||||||
Encoded Proteins |
SMT3 suppressor of mif two 3 homolog 1 (yeast)
SMT3 suppressor of mif two 3 homolog 1 (yeast)
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116030:
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 1:59586558-59670834 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | C2 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 669 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
SUMO is conjugated to E1 (UBA2:SAE1) pathway
SUMO is proteolytically processed pathway
SUMOylation pathway
Cytokine Signaling in Immune system pathway
Immune System pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Regulation of IFNG signaling pathway
SUMO is transferred from E1 to E2 (UBE2I, UBC9) pathway
Interferon gamma signaling pathway
Interferon Signaling pathway
Processing and activation of SUMO pathway
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KEGG |
RNA transport pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TGF_beta_Receptor pathway
TNFalpha pathway
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REACTOME |
Regulation of IFNG signaling pathway
Interferon gamma signaling pathway
Post-translational protein modification pathway
Cytokine Signaling in Immune system pathway
Processing and activation of SUMO pathway
Interferon Signaling pathway
Metabolism of proteins pathway
Immune System pathway
SUMO is transferred from E1 to E2 (UBE2I, UBC9) pathway
SUMO is conjugated to E1 (UBA2:SAE1) pathway
SUMO is proteolytically processed pathway
SUMOylation pathway
SUMO is proteolytically processed pathway
SUMOylation pathway
SUMO is transferred from E1 to E2 (UBE2I, UBC9) pathway
Cytokine Signaling in Immune system pathway
Interferon gamma signaling pathway
Immune System pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Interferon Signaling pathway
Regulation of IFNG signaling pathway
SUMO is conjugated to E1 (UBA2:SAE1) pathway
Processing and activation of SUMO pathway
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KEGG |
RNA transport pathway
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INOH | |||||||||||||||||||||||
PID NCI |
Signaling events mediated by HDAC Class I
Signaling events mediated by HDAC Class II
Sumoylation by RanBP2 regulates transcriptional repression
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.362118 | ||||||||||||||||||||||
RefSeq | NM_009460 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS35586 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||