Version 5.4
Mus musculus Gene: Lipg
Summary
InnateDB Gene IDBG-158621.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lipg
Gene Name lipase, endothelial
Synonyms 3110013K01Rik; EL; lipase; mEDL
Species Mus musculus
Ensembl Gene ENSMUSG00000053846
Encoded Proteins
IDBP-158623
lipase, endothelial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101670:
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:74939322-74961263
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000066532 ENSMUSP00000066536
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004465 lipoprotein lipase activity
GO:0004620 phospholipase activity
GO:0005515 protein binding
GO:0008201 heparin binding
GO:0008970 phosphatidylcholine 1-acylhydrolase activity
Biological Process
GO:0007584 response to nutrient
GO:0008283 cell proliferation
GO:0010983 positive regulation of high-density lipoprotein particle clearance
GO:0016042 lipid catabolic process
GO:0032376 positive regulation of cholesterol transport
GO:0034375 high-density lipoprotein particle remodeling
GO:0042632 cholesterol homeostasis
GO:0043691 reverse cholesterol transport
GO:0050746 regulation of lipoprotein metabolic process
GO:0055091 phospholipid homeostasis
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000101670
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
mmu00561
Glycerolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.299647
RefSeq NM_010720 XM_006525692
OMIM
CCDS CCDS29343
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca