InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cacng2

Summary

InnateDB Gene

IDBG-158634.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cacng2

Gene Name

calcium channel, voltage-dependent, gamma subunit 2

Synonyms

AW060990; B230105C07Rik; B930041E13Rik; stargazer; stargazin; stg; wag; waggler

Species

Mus musculus

Ensembl Gene

ENSMUSG00000019146

Encoded Proteins

IDBP-158636

calcium channel, voltage-dependent, gamma subunit 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166862:
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:77991748-78120028

Strand

Reverse strand

Band

Transcripts

ENSMUST00000019290

ENSMUSP00000019290

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005245	voltage-gated calcium channel activity
GO:0005515	protein binding
GO:0035255	ionotropic glutamate receptor binding

Biological Process

GO:0007528	neuromuscular junction development
GO:0019226	transmission of nerve impulse
GO:0042391	regulation of membrane potential
GO:0050877	neurological system process
GO:0051899	membrane depolarization
GO:0060081	membrane hyperpolarization
GO:0070588	calcium ion transmembrane transport
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Cellular Component

GO:0005891	voltage-gated calcium channel complex
GO:0016021	integral component of membrane
GO:0032281	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex