Version 5.4
Mus musculus Gene: Amica1
Summary
InnateDB Gene IDBG-159198.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Amica1
Gene Name adhesion molecule, interacts with CXADR antigen 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000048534
Encoded Proteins
IDBP-159200
adhesion molecule, interacts with CXADR antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160593:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:45079183-45108530
Strand Forward strand
Band A5.2
Transcripts
ENSMUST00000050020 ENSMUSP00000052033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0007157 heterophilic cell-cell adhesion
GO:0030593 neutrophil chemotaxis
GO:0035696 monocyte extravasation
GO:0046629 gamma-delta T cell activation
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0072672 neutrophil extravasation
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160593
View Gene Order
ENSBTAG00000023283
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_202937
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_225233
Cell surface interactions at the vascular wall pathway
REACT_230745
Immune System pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11152
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_12051
Cell surface interactions at the vascular wall pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
integrin_a4b1_pathway
Alpha4 beta1 integrin signaling events
Cross-References
SwissProt Q80UL9
TrEMBL
UniProt Splice Variant
Entrez Gene 270152
UniGene Mm.190461
RefSeq NM_001005421 XM_006510382 XM_006510383 XM_006510384 XM_006510385 XM_006510387
OMIM
CCDS CCDS23128
HPRD
IMGT
MGI ID MGI:2685484
MGI Symbol Amica1
EMBL AC122305 AY093688 BC050133
GenPept AAH50133 AAM15732
RNA Seq Atlas 270152

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca