Version 5.4
Mus musculus Gene: Cdc42ep1
Summary
InnateDB Gene IDBG-159968.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdc42ep1
Gene Name CDC42 effector protein (Rho GTPase binding) 1
Synonyms 1810058K22Rik; AA980734; Borg5; CEP1; MSE55
Species Mus musculus
Ensembl Gene ENSMUSG00000049521
Encoded Proteins
IDBP-159970
CDC42 effector protein (Rho GTPase binding) 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128283:
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:78842647-78850902
Strand Forward strand
Band E1
Transcripts
ENSMUST00000059619 ENSMUSP00000060930
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007266 Rho protein signal transduction
GO:0008360 regulation of cell shape
GO:0031274 positive regulation of pseudopodium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128283
View Gene Order
ENSBTAG00000030258
Not yet available
Cross-References
SwissProt Q91W92
TrEMBL
UniProt Splice Variant
Entrez Gene 104445
UniGene
RefSeq NM_027219
OMIM
CCDS CCDS27624
HPRD
IMGT
MGI ID MGI:1929763
MGI Symbol Cdc42ep1
EMBL AK007896 BC016250 BC083130
GenPept AAH16250 AAH83130 BAB25335
RNA Seq Atlas 104445

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca